In 2019, Covid-19 struck the world, leading to unprecedented changes in healthcare, reminiscent of the 1918 Spanish Flu pandemic, which impacted a third of the global population within a year. The pandemic presented major challenges to the healthcare system, requiring essential strategies for managing the outbreak, particularly in the care of critically ill patients. Nurses played a crucial role in the management of Covid-19. A cross sectional study was conducted by Clinical Nursing Research Society of India to identify the transformational roles performed by nurses at multi-centric settings to combat Covid-19 pandemic. The study also aims at identifying challenges faced by nurses during the performance of their roles. The data was collected from 664 nurses with the help of structured questionnaire on emerging role of nurses during Covid-19, roles related to crisis management, leadership skills and challenges faced by Nursing professionals. The study found that 50.3 percent of Nurses were able to take moderate level of emergent role of Nurses after Covid-19. Nurses had highest mean (SD) score in crisis management (13.37± 2.99) followed by emergent roles (10.55 ± 2.86) and leadership skills (5.77 ± 2.31) respectively.