Hospital-Acquired Anaemia (HAA) is very common but underappreciated risk of hospitalisation. Patients admitted with normal haemoglobin who subsequently develop HAA may be at risk for adverse outcomes and it is associated with modifiable factors like blood loss, bleeding, length of stay etc. So, we felt the need to conduct a study which throws a spotlight on the prevalence of HAA and to educate nurses about it. The present study sought to assess the prevalence and contributory factors of HAA and its contributory factors among patients admitted in selected Medical ICUs. It was an exploratory study conducted on 50 critically-ill patients admitted in selected Medical ICUs of a tertiary care hospital, Ludhiana selected by purposive sampling technique. The tool used was Socio-biodemographic profile, daily record sheet to assess haemoglobin levels as per WHO criteria for HAA (1968) and self-structured tool to explore contributory factors for HAA. Data was collected by self-report method and observation method. The findings revealed that 30 (60%) of the subjects under the study developed HAA among which 70 percent of the subjects had developed mild hospital acquired anaemia and 6.66 percent developed severe HAA. Majority of subjects developing HAA were males (n=23, 76.6%) with mean Hb 12.3±1.21 gm/dl as compared to females 7 (23.3%) with mean Hb 11.39±0.93 gm/dl (p=0.08). There was significant difference in haemoglobin levels from admission till discharge for subjects who developed HAA (13.6 vs 11.2 gm/dl, p=0.00). There was a significant association between the development of HAA and the consumption of nephrotoxic drugs (p=0.05) and PCV values (p=0.00). Significant association of HAA grades with investigational blood loss was observed (p=0.00). Prevalence of HAA among subjects was 60 percent with majority having mild HAA. HAA progresses with longer stay in hospital. There was a significant association of nephrotoxic drugs and reduced PCV with HAA. More the investigational blood loss, more was the severity of HAA.